LPA

LPA (Lysophosphatidic Acid): Lysophosphatidic acid (LPA) is a bioactive lipid molecule that serves as a potent signaling mediator involved in various physiological processes, including cell proliferation, migration, and survival. It exerts its effects by binding to specific G protein-coupled receptors, known as LPA receptors, present on the cell membrane. LPA is generated through the enzymatic hydrolysis of phospholipids, particularly phosphatidic acid, by phospholipase enzymes. In addition to its roles in normal cellular functions, LPA has been implicated in numerous pathological conditions, including cancer, fibrosis, and cardiovascular diseases. Its ability to promote cell proliferation and migration makes it a key player in...