RASSF3

RASSF3 (Ras Association Domain Family Member 3): RASSF3 is a member of the RASSF family of tumor suppressor proteins that play pivotal roles in cell cycle regulation, apoptosis, and cellular senescence. It functions as a key mediator of various signaling pathways, notably those involving the Ras proteins, which are critical for cell proliferation, differentiation, and survival. RASSF3's ability to interact with microtubules and other cellular structures further contributes to its involvement in the maintenance of genomic stability and the regulation of mitotic processes. The protein is implicated in the suppression of tumor growth and progression by inhibiting abnormal cell proliferation and inducing apoptosis in response to oncogenic signals. Loss of RASSF3 expression or its inactivation through genetic mutations can lead to uncontrolled cell growth and is associated with the development and progression of various cancers. Consequently, RASSF3 is considered a potential biomarker for cancer diagnosis and prognosis, as well as a target for therapeutic intervention in oncology.