PPIL1

PPIL1 (Peptidylprolyl Isomerase Like 1): PPIL1 is a member of the cyclophilin family of peptidylprolyl isomerases, enzymes that catalyze the cis-trans isomerization of proline imide bonds in polypeptides, thus facilitating protein folding and assembly. This enzymatic activity is crucial for various cellular processes, including signal transduction, transcriptional regulation, and cell cycle progression. PPIL1 is involved in the folding and function of proteins, contributing to the maintenance of cellular homeostasis and response to stress. It participates in several protein complexes and plays roles in the splicing of pre-mRNA, aiding in the precise regulation of gene expression. The involvement of PPIL1 in these fundamental processes underlines its importance in cellular physiology and its potential as a therapeutic target in diseases related to protein misfolding and dysfunction, such as neurodegenerative disorders. Additionally, its role in immune modulation and viral replication presents avenues for research in infectious diseases and immune therapies.