MYH6

MYH6 (Myosin Heavy Chain 6): MYH6 is a gene that encodes the alpha heavy chain subunit of cardiac myosin, a motor protein found in the heart muscle. This protein plays a fundamental role in the contraction of the cardiac muscle, enabling the heart to pump blood efficiently throughout the body. The alpha heavy chain is particularly important for the atrial contraction, contributing to the initial filling phase of the ventricles. Mutations in MYH6 have been linked to various cardiac disorders, including atrial septal defects, cardiomyopathies, and heart rhythm abnormalities, underscoring its critical role in cardiac function and development. The proper functioning of MYH6 is essential for maintaining the heart's pumping efficiency and rhythm, highlighting its importance in cardiovascular health. Understanding the genetic and molecular mechanisms of MYH6 can lead to improved diagnostics and therapeutic strategies for heart diseases associated with its dysregulation.