Kynurenic acid

Kynurenic acid is a metabolite produced in the kynurenine pathway, which is involved in the metabolism of the amino acid tryptophan. It is known for its role in the nervous system, where it acts as a neuroprotective agent. It's significant in neurological and psychiatric research, as imbalances are linked to conditions like schizophrenia and depression.

Kynurenic acid

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Who would benefit from testing their kynurenic acid levels?

Testing kynurenic acid levels can be beneficial for individuals with certain neurological or psychiatric conditions, such as schizophrenia, Alzheimer’s disease, or major depressive disorder. It may also be useful in research settings to better understand these disorders.

What are symptoms of high or low kynurenic acid?

High levels of kynurenic acid can lead to cognitive impairments and are linked to psychiatric disorders like schizophrenia. Low levels may contribute to neurodegenerative diseases like Alzheimer’s and increase susceptibility to excitotoxicity, potentially worsening mood disorders like depression.

What factors impact kynurenic acid levels?

Factors impacting kynurenic acid levels include:

  1. Genetic Variations: Genetic differences can affect the enzymes that regulate its production.
  2. Diet: Tryptophan intake influences its precursor availability.
  3. Inflammation: Immune responses can alter the kynurenine pathway, affecting kynurenic acid levels.
  4. Stress: Psychological stress can impact its synthesis.
  5. Disease States: Conditions like schizophrenia, Alzheimer’s, or depression can be associated with altered levels.
  6. Medications: Some drugs, especially those affecting the central nervous system, can influence kynurenic acid production.

How do you regulate your kynurenine acid levels?

Regulating kynurenic acid levels typically involves a holistic approach, focusing on overall health and well-being:

  1. Diet: A balanced diet, rich in essential nutrients, including tryptophan, can help.
  2. Manage Health Conditions: Addressing underlying health issues, especially inflammatory or neurological disorders.
  3. Stress Reduction: Techniques like mindfulness, meditation, or therapy can be beneficial.
  4. Exercise: Regular physical activity can positively influence overall metabolic pathways.
  5. Avoid Substance Abuse: Alcohol and certain drugs can disrupt these metabolic pathways.

Test(s) that measure/test for Kynurenic acid

No tests measure this item yet. But please contact our team to make sure this is the case... Sometimes we do test items, but it is just not added to be displayed here :)

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