GRIA1

GRIA1: GRIA1, or Glutamate Ionotropic Receptor AMPA Type Subunit 1, is a gene that encodes a key subunit of AMPA receptors, which are crucial for fast synaptic transmission in the brain. These receptors are responsive to the neurotransmitter glutamate, which is the most abundant excitatory neurotransmitter in the vertebrate nervous system. The GRIA1 subunit is integral in mediating synaptic plasticity, a foundation for learning and memory. Dysfunctions or mutations in GRIA1 have been implicated in various neurological disorders, including epilepsy and neurodegenerative diseases, making it a significant focus in neuroscience research.