GIGYF1

GIGYF1 (GRB10 Interacting GYF Protein 1): GIGYF1 is a critical adaptor protein involved in mediating cellular signaling pathways, particularly those associated with insulin receptor and IGF-1 receptor signaling. It interacts with the GRB10 protein, playing a pivotal role in the regulation of cell growth, differentiation, and metabolism. Through its involvement in these pathways, GIGYF1 contributes to the fine-tuning of insulin sensitivity and glucose homeostasis, implicating it in metabolic regulation and the pathophysiology of diabetes. Moreover, GIGYF1 has been linked to the regulation of mRNA translation and stability, underscoring its role in controlling gene expression at the post-transcriptional level. Dysregulation of GIGYF1 activity has been associated with various metabolic disorders, highlighting its potential as a therapeutic target for the treatment of diabetes and related metabolic diseases. The complexity of GIGYF1's interactions and functions emphasizes its significance in cellular physiology and disease.