Docosapentaenoic acid (DPA)

Docosapentaenoic acid (DPA) is a long-chain Omega-3 fatty acid less known than EPA and DHA but plays a significant role in health. Found in fish and seafood, DPA contributes to cardiovascular, cognitive, and overall health.

Docosapentaenoic acid (DPA)

What is docosapentaenoic acid (DPA)?

Docosapentaenoic acid (DPA) is an Omega-3 fatty acid found in marine oils, such as fish and seal oil, and is intermediate in structure between EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Although the body can convert DPA to either EPA or DHA, DPA itself has unique biological activities, contributing to cell membrane fluidity and function, and supporting cardiovascular and cognitive health.

Who would benefit from testing docosapentaenoic acid (DPA) levels?

Testing for DPA levels might be beneficial for:

  • Individuals with diets low in Omega-3 fatty acids, particularly those not consuming much fish.
  • People with a history of cardiovascular diseases, as DPA may have heart-protective properties.
  • Those experiencing cognitive decline or mood disorders, where Omega-3 fatty acids play a role.
  • Individuals interested in a comprehensive assessment of their fatty acid profile for overall health optimization.

What is the role of docosapentaenoic acid (DPA) in the body?

DPA acts as a critical component of cell membranes, influencing their fluidity and functionality. It plays a role in the cardiovascular system, potentially helping to reduce the risk of thrombosis and atherosclerosis. DPA may also have anti-inflammatory properties and contribute to brain health and cognitive functions, although its exact roles are less studied compared to EPA and DHA.

What are the symptoms of docosapentaenoic acid (DPA) deficiency?

  • Increased risk of cardiovascular issues.
  • Potential cognitive decline or impaired brain function.
  • Increased inflammation or immune system dysregulation.
  • Dry skin and hair.
  • Joint discomfort or stiffness.

Test(s) that measure/test for Docosapentaenoic acid (DPA)

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