CCDC141

CCDC141 (Coiled-Coil Domain Containing 141): CCDC141, characterized by its coiled-coil domain, is a protein implicated in the organization and function of cilia and flagella. These cellular structures are critical for movement, fluid flow, and signaling pathways in various cell types. CCDC141 plays a significant role in the proper formation and maintenance of cilia, influencing cellular processes such as motility, sensory perception, and developmental signaling pathways. Disruptions or mutations in the CCDC141 gene have been linked to ciliopathies, which are a group of disorders arising from dysfunctional cilia, affecting the kidneys, eyes, nervous system, and other organs. The study of CCDC141 provides insights into the fundamental mechanisms of ciliary function and its impact on human health, underscoring the protein's importance in cellular architecture and signaling. The regulation of CCDC141 and its involvement in ciliogenesis and ciliary function highlight its potential as a target for therapeutic intervention in diseases related to ciliary dysfunction.