CAV1

CAV1 (Caveolin-1): Caveolin-1 serves as a principal component of caveolae, small invaginations of the plasma membrane found in many vertebrate cell types. It is crucial for various cellular processes, including signal transduction, lipid metabolism, and endocytosis. CAV1 plays a significant role in modulating cellular signaling pathways by acting as a scaffolding protein that regulates the activity of numerous signaling molecules. Its involvement extends to the regulation of endothelial nitric oxide synthase (eNOS), which is essential for vascular tone and blood flow. Mutations and dysregulation of CAV1 expression have been linked to a variety of pathological conditions, including cancer, cardiovascular diseases, and pulmonary disorders. The multifaceted roles of CAV1 in cell signaling, membrane dynamics, and disease pathogenesis underscore its importance in cellular physiology and its potential as a target for therapeutic intervention.