AKR1A1

AKR1A1 (Aldo-keto reductase family 1 member A1): AKR1A1, a member of the aldo-keto reductase family, plays a pivotal role in cellular detoxification and metabolism. This enzyme catalyzes the reduction of various aldehydes and ketones, contributing to the regulation of oxidative stress and the detoxification of xenobiotics. AKR1A1 is involved in crucial physiological processes such as the metabolism of glucose and steroids, as well as the synthesis of prostaglandins and neurotransmitters. Its activity is essential for maintaining cellular homeostasis and protecting against oxidative damage. Dysregulation of AKR1A1 has been implicated in several pathological conditions including cancer, diabetes, and neurodegenerative diseases. Understanding the precise regulation of AKR1A1 function holds promise for developing targeted therapies for conditions related to cellular metabolism and detoxification.