Spermine is a polyamine derived from spermidine that plays a vital role in stabilising DNA, RNA, and cellular membranes. It contributes to antioxidant defence, inflammation control, and the regulation of cellular ageing. Elevated levels can occur during high metabolic or regenerative activity, while low levels may reflect reduced polyamine synthesis or increased cellular stress. Balanced spermine levels support optimal cellular integrity and protection against premature ageing.
Spermine is a polyamine derived from spermidine that plays a crucial role in stabilizing DNA, RNA, and cellular membranes. It supports antioxidant defense, regulates inflammation, and contributes to cellular repair and longevity.
Higher spermine levels may occur during periods of increased metabolic or regenerative activity. In some cases, elevated levels can also reflect a compensatory response to oxidative stress or tissue repair processes.
Low concentrations may point to reduced polyamine synthesis, nutrient deficiencies, or impaired cellular regeneration. They can also occur under chronic oxidative stress or aging-related decline in metabolic function.
Supporting polyamine metabolism through balanced nutrition, regular physical activity, and sufficient intake of polyamine precursors (such as arginine, methionine, and B vitamins) helps sustain optimal levels. Reducing oxidative stress and supporting mitochondrial health further promote cellular stability.