SLC45A2 (Solute Carrier Family 45 Member 2): SLC45A2 is a protein involved in melanin production, acting as a transporter of tyrosine, a key precursor in the melanin biosynthesis pathway. Variants of SLC45A2 contribute to human pigmentation differences, influencing skin, hair, and eye color. Mutations in this gene can cause oculocutaneous albinism type 4, characterized by reduced pigmentation and visual challenges. The function of SLC45A2 in pigmentation plays a role not only in physical appearance but also in protection against UV radiation and regulation of vitamin D synthesis.