SGK1 (Serum/Glucocorticoid Regulated Kinase 1): SGK1 is a serine/threonine kinase regulated by glucocorticoids, with roles in cell survival, ion transport, and metabolic regulation. It helps the body respond to stress and controls ion channel activity, particularly in the kidneys, influencing sodium and water balance. Dysregulation of SGK1 has been linked to hypertension, diabetic nephropathy, and certain cancers.