SDMA (Symmetric Dimethylarginine)
SDMA is a methylated derivative of the amino acid arginine and is mainly excreted by the kidneys. Unlike ADMA, SDMA does not directly inhibit nitric oxide synthase but reflects similar metabolic and renal processes. Elevated SDMA levels can indicate reduced kidney clearance or altered amino acid metabolism. Stable or optimal SDMA values suggest efficient renal function and normal arginine turnover.
Description
Elevated SDMA levels themselves may not cause noticeable symptoms, but they can reflect reduced kidney function or impaired amino acid metabolism. Individuals may experience fatigue, fluid retention, or other signs related to decreased renal clearance.
Testing SDMA is useful for anyone interested in assessing kidney health, particularly those with conditions like hypertension, diabetes, or cardiovascular disease. It can also be relevant for individuals using high-protein diets, supplements, or medications that may influence renal function.
SDMA concentrations are influenced by kidney filtration rate, protein turnover, and methylation activity. Impaired renal clearance or increased arginine methylation can elevate SDMA, while optimal hydration and metabolic balance help maintain stable levels.
In many cases, supporting kidney and metabolic health can help normalize SDMA. Maintaining adequate hydration, managing blood pressure and blood sugar, and reducing oxidative stress are key. A balanced diet and supporting methylation pathways may also play a role in keeping SDMA within a healthy range.
Trusted by over 100.000+ customers
The home test was straightforward with easy to follow instructions. The test result was detailed and clear in its presentation. Also had the opportunity to ask questions about the test result.
Richard
We looked at a lot of companies offering the same services but made the decision to go forward with get tested because the labs are based here in the UK. The process has been very straight forward.
Natasha
There are other providers out there, I have tried 3. Gettested was the fastest and the customer service was the best. I even received my test on the day of purchase delivered by a motorbike courier.
Alan
Absolutely perfect, results came after few days and finally after a lots of times visited GP, we finally know why my son has eczema - he is allergy to carrot. Thanks a lot.
E
I found them to be professional and not too long a wait for results. Helpful with any after questions. Will be using them again if need be. I highly recommend them.
Eileen