rs2129588: Similarly, rs2129588 is a single nucleotide polymorphism (SNP), a common type of genetic variation among individuals. Each SNP represents a change in a single DNA building block, or nucleotide, such as replacing cytosine (C) with thymine (T). Like other SNPs, rs2129588 can act as a biological marker, helping researchers identify genes associated with disease and supporting studies in genomics, pharmacogenomics, and population genetics.