PAX5
PAX5, also known as Paired Box 5, is a transcription factor that plays a crucial role in the regulation of B-cell development and differentiation. It belongs to the PAX family of transcription factors, characterized by the presence of a conserved paired box domain, which is involved in DNA binding and protein-protein interactions. One of the primary functions of PAX5 is its role in specifying B-cell lineage commitment during hematopoiesis, the process by which blood cells are formed. PAX5 is expressed in progenitor cells committed to the B-cell lineage and is essential for the development of B cells from hematopoietic stem cells....
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