FSHR
FSHR, or Follicle-Stimulating Hormone Receptor, is a G protein-coupled receptor (GPCR) primarily expressed on the surface of ovarian granulosa cells in females and Sertoli cells in males. It plays a crucial role in the regulation of reproductive function by mediating the effects of follicle-stimulating hormone (FSH), a glycoprotein hormone secreted by the anterior pituitary gland. One of the primary functions of FSHR is its role in folliculogenesis, the process by which ovarian follicles develop and mature. In females, FSH binds to FSHR on granulosa cells within ovarian follicles, leading to a cascade of intracellular signaling events that promote follicle growth, proliferation,...
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