CRTC3 (CREB Regulated Transcription Coactivator 3): CRTC3 is a gene that encodes a coactivator protein involved in transcriptional regulation. It works by interacting with CREB (cAMP response element-binding protein) to modulate gene expression in response to different signaling pathways. CRTC3 plays important roles in maintaining cellular energy balance, metabolism, and glucose homeostasis.