TYMS

The TYMS gene encodes thymidylate synthase, a key enzyme involved in the synthesis of thymidine, one of the four nucleotides required for DNA replication and repair. This enzyme relies on active folate (5,10-methylene-THF) to function efficiently, linking TYMS closely to folate metabolism. Variants in the TYMS gene can affect folate availability at the cellular level and may alter how the body responds to folate or folate-based therapies. Such changes may contribute to impaired DNA synthesis, increased susceptibility to certain diseases, or variable responses to chemotherapy or supplementation.

No image found

Description

What does the TYMS gene do?

TYMS encodes thymidylate synthase, an enzyme necessary for producing thymidine used in DNA synthesis and repair.

How is TYMS related to folate metabolism?

The enzyme uses active folate as a cofactor, so folate status significantly affects TYMS activity.

What happens if you have a TYMS variant?

Certain variants may reduce enzyme efficiency, impacting DNA replication and folate utilization.

Can TYMS variants affect health or treatment outcomes?

Yes, they may influence susceptibility to disease or the effectiveness of folate-related therapies, including certain chemotherapeutic agents.

Your Cart

Content
What does the TYMS gene do?
How is TYMS related to folate metabolism?
What happens if you have a TYMS variant?
Can TYMS variants affect health or treatment outcomes?
What does the TYMS gene do?
How is TYMS related to folate metabolism?
What happens if you have a TYMS variant?
Can TYMS variants affect health or treatment outcomes?
girl-img

Trusted by over 100.000+ customers

star-image
card-swiper-image
star-image

The home test was straightforward with easy to follow instructions. The test result was detailed and clear in its presentation. Also had the opportunity to ask questions about the test result.

Richard

card-swiper-image
star-image

We looked at a lot of companies offering the same services but made the decision to go forward with get tested because the labs are based here in the UK. The process has been very straight forward.

Natasha

card-swiper-image
star-image

There are other providers out there, I have tried 3. Gettested was the fastest and the customer service was the best. I even received my test on the day of purchase delivered by a motorbike courier.

Alan

card-swiper-image
star-image

Absolutely perfect, results came after few days and finally after a lots of times visited GP, we finally know why my son has eczema - he is allergy to carrot. Thanks a lot.

E

card-swiper-image
star-image

I found them to be professional and not too long a wait for results. Helpful with any after questions. Will be using them again if need be. I highly recommend them.

Eileen