Succinate is a key metabolic intermediate that plays an essential role in the Krebs cycle, the process by which cells produce energy. It helps convert nutrients into ATP, the primary energy source for cellular functions. Beyond energy production, succinate also participates in amino acid and fatty acid synthesis and acts as a signaling molecule that influences inflammation and the body’s response to low oxygen levels.
Testing succinate levels might benefit from this testing:
Dysregulated succinate levels, particularly when elevated, can be associated with various symptoms, often reflecting underlying metabolic or mitochondrial dysfunction. The specific symptoms can vary depending on the extent and nature of the metabolic disruption. Common symptoms might include:
Regulating succinate levels in the body, particularly when addressing elevated levels due to metabolic or mitochondrial disorders, involves managing the underlying condition. Some general strategies can support healthy metabolic function, which in turn can help maintain appropriate succinate levels:
Several factors can affect succinate levels in the body, primarily related to metabolic processes and overall health. Key factors include: