By analyzing organic acids, one can get an overview of the use of nutrients that are ingested through food as well as their conversion to energy (ATP). This conversion is performed using enzymes and their cofactors. If these cofactors are missing or if the enzymes do not work optimally, it can lead to the accumulation of certain substances. The concentration of these substances makes it possible to read what deficiencies in vitamins and minerals may be present. In addition, metabolic products of neurotransmitters in the urine may indicate disturbances in the stress hormone balance and dysbiosis markers may reflect a bacterial imbalance in the intestine.
As the sample is taken via urine, it is a test that is also suitable for children.
What is measured in the organic acids test?
The test measures the following markers:
Lipometabolism | Indicates |
---|---|
Adipate | Carnitine, B2 deficiency |
Suberate | Carnitine, B2 deficiency |
Etylmalonat | Carnitine, B2 deficiency |
Carbohydrate metabolism | |
Lactate | Glycolysis |
Pyruvat | Increased utilization of anaerobic energy development, disordered mitochondrial function, deficiency of B6, B3 and lipoic acid |
ß-Hydroxi-butyrat | Ketone production |
Organic acids in the citric acid cycle | |
Cis-akonitat | Magnesium and manganese deficiency |
Citrat | Nitrosative stress |
Isocitrat | Magnesium and manganese deficiency |
Hydroxy-dimethylglutarate | Coenzyme Q10 deficiency and fungal infection of the intestine |
Succinat | B2, B3, B12 and biotin deficiency |
α-ketoglutarat | α-lipoic acid, B1, B2, B3, B5, B6 and magnesium deficiency |
Fumarat | Catabolic metabolism and B2 deficiency |
Malat | Q10 and B3 deficiency |
Organic acids of vitamin metabolism | |
α-keto-isovalerate | B1, B2, B3, B5, B6, β-lipoic acid and magnesium deficiency |
Xanthurenat | B6 deficiency |
Methylmalonic acid | B12 deficiency |
Degradation of neurotransmitters | |
Vanillyl mandelic acid | Metabolism of adrenaline and noradrenaline |
Homo-vanillyl mandelic acid | Dopamine metabolism |
5-hydroxyindole acetate | Serotonin metabolism |
Kynurenate | Tryptophan “pathway” |
Dysbiosis markers | |
D-Arabinitol | Systemic candida infection |
Hydroxybenzoic acid | Microbial overgrowth |
Citramalat | Yeast and population of anaerobic bacteria |
How the test is performed
The test is a simple urine sample that you collect yourself at home in the morning from your morning urine. The sample is then sent to the lab for analysis and you will receive your answer digitally.
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