Spermidine is a naturally occurring polyamine involved in cellular growth, repair, and protection. It supports autophagy — the body’s natural process of clearing damaged cells — and contributes to mitochondrial function and longevity pathways. Higher levels are often associated with enhanced cellular renewal and resilience against oxidative stress. Low concentrations may indicate reduced cell turnover, nutritional insufficiency, or increased oxidative demands.
Spermidine is a naturally occurring polyamine that supports cellular growth, repair, and protection. It promotes autophagy – the body’s process of clearing damaged cells – and contributes to mitochondrial efficiency, metabolic balance, and longevity pathways.
Spermidine levels are influenced by diet, gut microbial activity, and metabolic health. Foods such as wheat germ, soybeans, mushrooms, and aged cheese are natural sources, while oxidative stress, aging, and nutrient deficiencies can lower levels.
Testing can be valuable for individuals interested in longevity, cellular health, or oxidative stress balance. It may also help identify impaired autophagy or reduced metabolic resilience.
Yes. A nutrient-rich diet, adequate sleep, physical activity, and supporting gut microbial diversity all help sustain healthy spermidine production. Reducing oxidative stress and maintaining balanced polyamine metabolism further promote optimal cellular renewal.