SMARCA2 (SWI/SNF-Related, Matrix-Associated, Actin-Dependent Regulator of Chromatin, Subfamily A, Member 2): SMARCA2 is a gene that encodes a core component of the SWI/SNF chromatin remodeling complex. It plays a key role in regulating gene expression by modifying chromatin structure. Mutations in SMARCA2 are linked to disorders such as Nicolaides-Baraitser syndrome, which involves intellectual disability and sparse hair. Its function is essential for proper gene regulation and development.