SLK
SLK, also known as STE20-like kinase, is a key enzyme belonging to the serine/threonine kinase family. Positioned primarily within the cytoplasm of cells, SLK plays a pivotal role in regulating various cellular processes, including cell proliferation, survival, migration, and cytoskeletal organization. One of the distinguishing features of SLK is its involvement in signaling pathways that govern cell morphology and motility. Through its kinase activity, SLK phosphorylates target proteins involved in cytoskeletal dynamics, such as focal adhesion kinase (FAK), paxillin, and cortactin, thereby modulating the assembly and turnover of focal adhesions and actin stress fibers. Moreover, SLK has been implicated in the regulation...
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