PPP3CA (Protein Phosphatase 3 Catalytic Subunit Alpha): PPP3CA is a gene that encodes the catalytic subunit alpha of protein phosphatase 3 (PP3), also known as calcineurin. Calcineurin is a calcium-dependent enzyme involved in signaling pathways that regulate immune responses and various cellular processes, including gene expression. The activity of PPP3CA plays a key role in dephosphorylating target proteins, thereby influencing multiple cellular functions.