LPL (Lipoprotein Lipase): LPL is a gene that encodes an enzyme essential for the metabolism of triglyceride-rich lipoproteins. It hydrolyzes triglycerides in lipoproteins such as chylomicrons and VLDL, enabling the release of free fatty acids for energy use or storage. Mutations in LPL can lead to hyperlipidemia and increase the risk of pancreatitis and cardiovascular disease.