IL18R1 (Interleukin 18 Receptor 1): IL18R1 is a protein that acts as a receptor for interleukin 18 (IL-18), a cytokine involved in inflammation and immune defense. IL18R1 plays a key role in the immune response by enabling the activation of natural killer cells and specific T-cells, which are essential for fighting infection and injury. Changes in the IL18R1 gene can affect susceptibility to inflammatory and autoimmune diseases, underscoring its role in regulating immune and inflammatory processes.