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CBLB (C-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase): CBLB is a gene that encodes an E3 ubiquitin ligase protein involved in regulating intracellular signaling pathways by targeting proteins for degradation. It plays a role in immune responses, particularly by negatively regulating T cell activation. Dysregulation of CBLB may contribute to autoimmune diseases and other immune-related disorders.

